miniature,--just as the faculty itself is really a specification of the entire man, a sort of homunculus.
Yet just such homunculi are for the most part the phrenological organs.
As Lange says: "We have a parliament of little men together, each one of whom, as happens also in a real parliament, possesses but a single idea which he ceaselessly strives to make prevail"--benevolence, firmness, hope, and the rest. "Instead of one soul, phrenology gives us forty, each alone as enigmatic as the full aggregate psychic life can be. Instead of dividing the latter into effective elements, she divides it into personal beings of peculiar character...'Herr Pastor, sure there be a horse inside,' called out the peasants to X after their spiritual shepherd had spent hours in explaining to them the construction of the locomotive. With a horse inside truly everything becomes clear, even though it be a queer enough sort of horse--the horse itself calls for no explanation! Phrenology takes a start to get beyond the point of view of the ghost-like soul entity, but she ends by populating the whole skull with ghosts of the same order."[8] Modern Science conceives of the matter in a very different way. _Brain and mind alike consist of simple elements, sensory and motor_. "All nervous centres," says Dr. Hughlings Jackson,[9] "from the lowest to the very highest (the substrata of consciousness), are made up of nothing else than nervous arrangements, representing impressions and movements...I do not see of what other materials the brain _can_ be made." Meynert represents the matter similarly when he calls the cortex of the hemispheres the surface of projection for every muscle and every sensitive point of the body. The muscles and the sensitive points are _represented_ each by a cortical point, and the brain is nothing but the sum of all these cortical points, to which, on the mental side, as many _ideas_ correspond. _Ideas of sensation, ideas of motion_ are, on the other hand, _the elementary factors out of which the mind is built up by the associationists in psychology_. There is a complete parallelism between the two analyses, the same diagram of little dots, circles, or triangles joined by lines symbolizes equally well the cerebral and mental processes: the dots stand for cells or ideas, the lines for fibres or associations. We shall have later to criticise this analysis so far as it relates to the mind; but there is no doubt that it is a most convenient, and has been a most useful, hypothesis, formulating the facts in an extremely natural way.
If, then, we grant that motor and sensory ideas variously associated are the materials of the mind, all we need do to get a complete diagram of the mind's and the brain's relations should be to ascertain which sensory idea corresponds to which sensational surface of projection, and which motor idea to which muscular surface of projection. The associations would then correspond to the fibrous connections between the various surfaces. This distinct _cerebral localization_ of the various elementary sorts of idea has been treated as a 'postulate' by many physiologists (e.g. Munk); and the most stirring controversy in nerve-physiology which the present generation has seen has been the THE LOCALIZATION OF FUNCTIONS IN THE HEMISPHERES.
Up to 1870, the opinion which prevailed was that which the experiments of Flourens on pigeons' brains had made plausible, namely, that the different functions of the hemispheres were not locally separated, but carried on each by the aid of the whole organ. Hitzig in 1870 showed, however, that in a dog's brain highly specialized movements could be produced by electric irritation of determinate regions of the cortex; and Ferrier and Munk, half a dozen years later, seemed to prove, either by irritations or excisions or both, that there were equally determinate regions connected with the senses of sight, touch, hearing, and smell. Munk's special sensorial localizations, however, disagreed with Ferrier's; and Goltz, from his extirpation-experiments, came to a conclusion adverse to strict localization of any kind. The controversy is not yet over. I will not pretend to say anything more of it historically, but give a brief account of the condition in which matters at present stand.
The one thing which is _perfectly_ well established is this, that the 'central' convolutions, on either side of the fissure of Rolando, and (at least in the monkey) the calloso-marginal convolution (which is continuous with them on the mesial surface where one hemisphere is applied against the other), form the region by which all the motor incitations which leave the cortex pass out, on their way to those executive centres in the region of the pons, medulla, and spinal cord from which the muscular contractions are discharged in the last resort.
The existence of this so-called 'motor zone' is established by the lines of evidence successively given below: (1) _Cortical Irritations._ Electrical currents of small intensity applied to the surface of the said convolutions in dogs, monkeys, and other animals, produce well-defined movements in face, fore-limb, hind-limb, tail, or trunk, according as one point or another of the surface is irritated. These movements affect almost invariably the side opposite to the brain irritations: If the left hemisphere be excited, the movement is of the right leg, side of face, etc. All the objections at first raised against the validity of these experiments have been overcome. The movements are certainly not due to irritations of the base of the brain by the downward spread of the current, for: _a_) mechanical irritations will produce them, though less easily than electrical; _b_) shifting the electrodes to a point close by on the surface changes the movement in ways quite inexplicable by changed physical conduction of the current; _c_) if the cortical 'centre' for a certain movement be cut under with a sharp knife but left _in situ_, although the electric conductivity is physically unaltered by the operation, the physiological conductivity is gone and currents of the same strength no longer produce the movements which they did; _d_) the time-interval between the application of the electric stimulus to the cortex and the resultant movement is what it would be if the cortex acted physiologically and not merely physically in transmitting the irritation. It is namely a well-known fact that when a nerve-current has to pass through the spinal cord to excite a muscle by reflex action, the time is longer than if it passes directly down the motor nerve: the cells of the cord take a certain time to discharge.
Similarly, when a stimulus is applied directly to the cortex the muscle contracts two or three hundredths of a second later than it does when the place on the cortex is cut away and the electrodes are applied to the white fibres below.[10] (2) _Cortical Ablations._ When the cortical spot which is found to produce a movement of the fore-leg, in a dog, is excised (see spot 5 in Fig. 5), the leg in question becomes peculiarly affected. At first it seems paralyzed. Soon, however, it is used with the other legs, but badly. The animal does not bear his weight on it, allows it to rest on its dorsal surface, stands with it crossing the other leg, does not remove it if it hangs over the edge of a table, can no longer 'give the paw' at word of command if able to do so before the operation, does not use it for scratching the ground, or holding a bone as formerly, lets it slip out when running on a smooth surface or when shaking himself, etc., etc. Sensibility of all kinds seems diminished as well as motility, but of this I shall speak later on. Moreover the dog tends in voluntary movements to swerve towards the side of the brain-lesion instead of going straight forward. All these symptoms gradually decrease, so that even with a very severe brain-lesion the dog may be outwardly indistinguishable from a well dog after eight or ten weeks.
Still, a slight chloroformization will reproduce the disturbances, even then. There is a certain appearance of ataxic in-coordination in the movements--the dog lifts his fore-feet high and brings them down with more strength than usual, and yet the trouble is not ordinary lack of co-ordination. Neither is there paralysis. The strength of whatever movements are made is as great as ever--dogs with extensive destruction of the motor zone can jump as high and bite as hard as ever they did, but they seem _less easily moved_ to do _anything_ with the affected parts. Dr. Loeb, who has studied the motor disturbances of dogs more carefully than any one, conceives of them _en masse_ as effects of an increased inertia in all the processes of innervation towards the side opposed to the lesion. All such movements require an unwonted effort for their execution; and when only the normally usual effort is made they fall behind in effectiveness.[11] Even when the entire motor zone of a dog is removed, there is no permanent paralysis of any part, but only this curious sort of relative inertia when the two sides of the body are compared; and this itself becomes hardly noticeable after a number of weeks have elapsed. Prof.
Goltz has described a dog whose entire left hemisphere was destroyed, and who retained only a slight motor inertia on the right half of the body. In particular he could use his right paw for holding a bone whilst gnawing it, or for reaching after a piece of meat. Had he been taught to give his paw Before the operations, it would have been curious to see whether that faculty also came back. His tactile sensibility was permanently diminished on the right side.[12] In _monkeys_ a genuine paralysis follows upon ablations of the cortex in the motor region. This paralysis affects parts of the body which vary with the brain-parts removed. The monkey's opposite arm or leg hangs flaccid, or at most takes a small part in associated movements.
When the entire region is removed there is a genuine and permanent hemiplegia in which the arm is more affected than the leg; and this is followed months later by contracture of the muscles, as in man after inveterate hemiplegia.[13] According to Schaefer and Horsley, the trunk-muscles also become paralyzed after destruction of the _marginal_ convolution on _both_ sides (see Fig. 7). These differences between dogs and monkeys show the danger of drawing general conclusions from experiments done on any one sort of animal. I subjoin the figures given by the last-named authors of the motor regions in the monkey's brain.[14] _In man_ we are necessarily reduced to the observation _post-mortem_ of cortical ablations produced by accident or disease (tumor, hemorrhage, softening, etc.). What results during life from such conditions is either localized spasm, or palsy of certain muscles of the opposite side. The cortical regions which invariably produce these results are homologous with those which we have just been studying in the dog, cat, ape, etc. Figs. 8 and 9 show the result of 169 cases carefully studied by Exner. The parts shaded are regions where lesions produced _no_ motor disturbance. Those left white were, on the contrary, never injured without motor disturbances of some sort. Where the injury to the cortical substance is profound in man, the paralysis is permanent and is succeeded by muscular rigidity in the paralyzed parts, just as it may be in the monkey.
(3) _Descending degenerations_ show the intimate connection of the rolandic regions of the cortex with the motor tracts of the cord. When, either in man or in the lower animals, these regions are destroyed, a peculiar degenerative change known as secondary sclerosis is found to extend downwards through the white fibrous substance of the brain in a perfectly definite manner, affecting certain distinct strands which pass through the inner capsule, crura, and pons, into the anterior pyramids of the medulla oblongata, and from thence (partly crossing to the other side) downwards into the anterior (direct) and lateral (crossed) columns of the spinal cord.
(4) _Anatomical proof_ of the continuity of the rolandic regions with these motor columns of the cord is also clearly given. Flechsig's 'Pyramidenbahn' forms an uninterrupted strand (distinctly traceable in human embryos, before its fibres have acquired their white 'medullary sheath') passing upwards from the pyramids of the medulla, and traversing the internal capsule and corona radiata to the convolutions in question (Fig. 10). None of the inferior gray matter of the brain seems to have any connection with this important fibrous strand. It passes directly from the cortex to the motor arrangements in the cord, depending for its proper nutrition (as the facts of degeneration show) on the influence of the cortical cells, just as motor nerves depend for their nutrition on that of the cells of the spinal cord. Electrical stimulation of this motor strand in any accessible part of its course has been shown in dogs to produce movements analogous to those which excitement of the cortical surface calls forth.
One of the most instructive proofs of motor localization in the cortex is that furnished by the disease now called aphemia, or _motor Aphasia_. Motor aphasia is neither loss of voice nor paralysis of the tongue or lips. The patient's voice is as strong as ever, and all the innervations of his hypoglossal and facial nerves, except those necessary for speaking, may go on perfectly well. He can laugh and cry, and even sing; but he either is unable to utter any words at all; or a few meaningless stock phrases form his only speech; or else he speaks incoherently and confusedly, mispronouncing, misplacing, and misusing his words in various degrees. Sometimes his speech is a mere broth of unintelligible syllables. In cases of pure motor aphasia the patient recognizes his mistakes and suffers acutely from them. Now whenever a patient dies in such a condition as this, and an examination of his brain is permitted, it is found that the lowest frontal gyrus (see Fig. 11) is the seat of injury. Broca first noticed this fact in 1861, and since then the gyrus has gone by the name of Broca's convolution. The injury in right-handed people is found on the left hemisphere, and in left-handed people on the right hemisphere.
Most people, in fact, are left-brained, that is, all their delicate and specialized movements are handed over to the charge of the left hemisphere. The ordinary right-handedness for such movements is only a consequence of that fact, a consequence which shows outwardly on account of that extensive decussation of the fibres whereby most of those from the left hemisphere pass to the right half of the body only.
But the left-brainedness might exist in equal measure and not show outwardly. This would happen wherever organs on _both_ sides of the body could be governed by the left hemisphere; and just such a case seems offered by the vocal organs, in that highly delicate and special motor service which we call speech. Either hemisphere _can_ innervate them bilaterally, just as either seems able to innervate bilaterally the muscles of the trunk, ribs, and diaphragm. Of the special movements of speech, however, it would appear (from the facts of aphasia) that the left hemisphere in most persons habitually takes exclusive charge.
With that hemisphere thrown out of gear, speech is undone; even though the opposite hemisphere still be there for the performance of less specialized acts, such as the various movements required in eating.
It will be noticed that Broca's region is homologous with the parts ascertained to produce movements of the lips, tongue, and larynx when excited by electric currents in apes (cf. Fig. 6). The evidence is therefore as complete as it well can be that the motor incitations to these organs leave the brain by the lower frontal region.
Victims of motor aphasia generally have other disorders. One which interests us in this connection has been called _agraphia_: they have lost the power to _write_. They can read writing and understand it; but either cannot use the pen at all or make egregious mistakes with it. The seat of the lesion here is less well determined, owing to an insufficient number of good cases to conclude from.[15] There is no doubt, however, that it is (in right-handed people) on the left side, and little doubt that it consists of elements of the hand-and-arm region specialized for that service, The symptom may exist when there is little or no disability in the hand for other uses. If it does not get well, the patient usually educates his right hemisphere, i.e.
learns to write with his left hand. In other cases of which we shall say more a few pages later on, the patient can write both spontaneously and at dictation, but cannot _read_ even what he has himself written!
All these phenomena are now quite clearly explained by separate brain-centres for the various feelings and movements and tracts for associating these together. But their minute discussion belongs to medicine rather than to general psychology, and I can only use them here to illustrate the principles of motor localization.[16] Under the heads of sight and hearing I shall have a little more to say.
The different lines of proof which I have taken up establish conclusively the proposition that _all the motor impulses which leave the cortex pass out_, in healthy animals, _from the convolutions about the fissure of Rolando_.
When, however, it comes to defining precisely what is involved in a motor impulse leaving the cortex, things grow more obscure. Does the impulse start independently from the convolutions in question, or does it start elsewhere and merely flow through? And to what particular phase of psychic activity does the activity of these centres correspond? Opinions and authorities here divide; but it will be better, before entering into these deeper aspects of the problem, to cast a glance at the facts which have been made out concerning the relations of the cortex to sight, hearing, and smell.
_Sight._ Ferrier was the first in the field here. He found, when the _angular_ convolution (that lying between the 'intra parietal' and 'external occipital' fissures, and bending round the top of the fissure of Sylvius, in Fig. 6) was excited in the monkey, that movements of the eyes and head as if for vision occurred; and that when it was extirpated, what he supposed to be total and permanent blindness of the opposite eye followed. Munk almost immediately declared total and permanent blindness to follow from destruction of the _occipital lobe_ in monkeys as well as dogs, and said that the angular gyrus had nothing to do with sight, but was only the centre for tactile sensibility of the eyeball. Hunk's absolute tone about his observations and his theoretic arrogance have led to his ruin as an authority. But he did two things of permanent value. He was the first to distinguish in these vivisections between sensorial and _psychic_ blindness, and to describe the phenomenon of _restitution_ of the visual function after its first impairment by an operation; and the first to notice the _hemiopic_ character of the visual disturbances which result when only one hemisphere is injured. Sensorial blindness is absolute insensibility to light; psychic blindness is inability to recognize the _meaning_ of the optical impressions, as when we see a page of Chinese print but it suggests nothing to us. A hemiopic disturbance of vision is one in which neither retina is affected in its totality, but in which, for example, the left portion of _each_ retina is blind, so that the animal sees nothing situated in space towards its right. Later observations have corroborated this hemiopic character of all the disturbances of sight from injury to a single hemisphere in the higher animals; and the question whether an animal's apparent blindness is sensorial or only psychic has, since Munk's first publications, been the most urgent one to answer, in all observations relative to the function of sight.
Goltz almost simultaneously with Ferrier and Munk reported experiments which led him to deny that the visual function was essentially bound up with any one localized portion of the hemispheres. Other divergent results soon came in from many quarters, so that, without going into the history of the matter any more, I may report the existing state of the case as follows:[17] In _fishes, frogs_, and _lizards_ vision persists when the hemispheres are entirely removed. This is admitted for frogs and fishes even by Munk, who denies it for birds.
All of Munk's _birds_ seemed totally blind (blind sensorially) after removal of the hemispheres by his operation. The following of a candle by the head and winking at a threatened blow, which are ordinarily held to prove the retention of crude optical sensations by the lower centres in supposed hemisphereless pigeons, are by Munk ascribed to vestiges of the visual sphere of the cortex left behind by the imperfection of the operation. But Schrader, who operated after Munk and with every apparent guarantee of completeness, found that all his pigeons saw after two or three weeks had elapsed, and the inhibitions resulting from the wound had passed away. They invariably avoided even the slightest obstacles, flew very regularly towards certain perches, etc., differing _toto cœlo_ in these respects with certain simply _blinded_ pigeons who were kept with them for comparison. They did not pick up food strewn on the ground, however. Schrader found that they would do this if even a small part of the frontal region of the hemispheres was left, and ascribes their non-self-feeding when deprived of their occipital cerebrum not to a visual, but to a motor, defect, a sort of alimentary aphasia.[18] In presence of such discord as that between Munk and his opponents one must carefully note how differently significant is _loss_, from _preservation_, of a function after an operation on the brain. The _loss_ of the function does not necessarily show that it _is_ dependent on the part cut out; but its _preservation_ does show that it is _not_ dependent: and this is true though the loss should be observed ninety-nine times and the preservation only once in a hundred similar excisions. That birds and mammals _can_ be blinded by cortical ablation is undoubted; the only question is, _must_ they be so? Only then can the cortex be certainly called the 'seat of sight.' The blindness may always be due to one of those remote effects of the wound on distant parts, inhibitions, extensions of inflammation,--interferences, in a word,--upon which Brown-Séquard and Goltz have rightly insisted, and the importance of which becomes more manifest every day. Such effects are transient; whereas the _symptoms of deprivation_ (_Ausfallserscheinungen_, as Goltz calls them) which come from the actual loss of the cut-out region must from the nature of the case be permanent. Blindness in the pigeons, _so far as it passes away_, cannot possibly be charged to their seat of vision being lost, but only to some influence which temporarily depresses the activity of that seat. The same is true _mutatis mutandis_ of all the other effects of operations, and as we pass to mammals we shall see still more the importance of the remark.
_In rabbits_ loss of the entire cortex seems compatible with the preservation of enough sight to guide the poor animals' movements, and enable them to avoid obstacles. Christiani's observations and discussions seem conclusively to have established this, although Munk found that all _his_ animals were made totally blind.[19] _In dogs_ also Munk found absolute stone-blindness after ablation of the occipital lobes. He went farther and mapped out determinate portions of the cortex thereupon, which he considered correlated with definite segments of the two retinæ, so that destruction of given portions of the cortex produces blindness of the retinal centre, top, bottom, or right or left side, of the same or opposite eye. There seems little doubt that this definite correlation is mythological.
Other observers, Hitzig, Goltz, Luciani, Loeb, Exner, etc., find, whatever part of the cortex may be ablated on one side, that there usually results a _hemiopic_ disturbance of _both_ eyes, slight and transient when the anterior lobes are the parts attacked, grave when an occipital lobe is the seat of injury, and lasting in proportion to the latter's extent. According to Loeb, the defect is a dimness of vision ('hemiamblyopia') in which (however severe) the centres remain the best seeing portions of the retina, just as they are in normal dogs.
The lateral or temporal part of each retina seems to be in exclusive connection with the cortex of its own side. The centre and nasal part of each seems, on the contrary, to be connected with the cortex of the opposite hemispheres. Loeb, who takes broader views than any one, conceives the hemiamblyopia as he conceives the motor disturbances, namely, as the expression of an increased inertia in the whole optical machinery, of which the result is to make the animal respond with greater effort to impressions coming from the half of space opposed to the side of the lesion. If a dog has right hemiamblyopia, say, and two pieces of meat are hung before him at once, he invariably turns first to the one on his left. But if the lesion be a slight one, _shaking_ slightly the piece of meat on his right (this makes of it a stronger stimulus) makes him seize upon it first. If only one piece of meat be offered, he takes it, on whichever side it be.
When both occipital lobes are extensively destroyed total blindness may result. Munk maps out his 'Sehsphäre' definitely, and says that blindness _must_ result when the entire shaded part, marked _A, A,_ in Figs. 12 and 13, is involved in the lesion. Discrepant reports of other observations he explains as due to incomplete ablation. Luciani, Goltz, and Lannegrace, however, contend that they have made complete bilateral extirpations of Munk's Sehsphäre more than once, and found a sort of crude indiscriminating sight of objects to return in a few weeks.[20] The question whether a dog is blind or not is harder to solve than would at first appear; for simply blinded dogs, in places to which they are accustomed, show little of their loss and avoid all obstacles; whilst dogs whose occipital lobes are gone may run against things frequently and yet see notwithstanding. The best proof that they may see is that which Goltz's dogs furnished: they carefully avoided, as it seemed, strips of sunshine or paper on the floor, as if they were solid obstacles. This no really blind dog would do. Luciani tested his dogs when hungry (a condition which sharpens their attention) by strewing pieces of meat and pieces of cork before them. If they went straight at them, they _saw_; and if they chose the meat and left the cork, they _saw discriminatingly_. The quarrel is very acrimonious; indeed the subject of localization of functions in the brain seems to have a peculiar effect on the temper of those who cultivate it experimentally.
The amount of preserved vision which Goltz and Luciani report seems hardly to be worth considering, on the one hand; and on the other, Munk admits in his penultimate paper that out of 85 dogs he only 'succeeded' 4 times in his operation of producing complete blindness by complete extirpation of his 'Sehsphäre.'[21] The safe conclusion for _us_ is that Luciani's diagram, Fig. 14, represents something like the truth.
The occipital lobes are far more important for vision than any other part of the cortex, so that their complete destruction makes the animal almost blind. As for the crude sensibility to light which _may_ then remain, nothing exact is known either about its nature or its seat.
_In the monkey_, doctors also disagree. The truth seems, however, to be that the _occipital lobes_ in this animal also are the part connected most intimately with the visual function. The function would seem to go on when very small portions of them are left, for Ferrier found no 'appreciable impairment' of it after almost complete destruction of them on both sides. On the other hand, he found complete and permanent blindness to ensue when they and the _angular gyri_ in addition were destroyed on both sides. Munk, as well as Brown and Schaefer, found no disturbance of sight from destroying the _angular gyri_ alone, although Ferrier found blindness to ensue. This blindness was probably due to inhibitions exerted _in distans_, or to cutting of the white optical fibres passing under the angular gyri on their way to the occipital lobes. Brown and Schaefer got complete and permanent blindness in one monkey from total destruction of both occipital lobes. Luciani and Seppili, performing this operation on two monkeys, found that the animals were only mentally, not sensorially, blind. After some weeks they saw their food, but could not distinguish by sight between figs and pieces of cork. Luciani and Seppili seem, however, not to have extirpated the entire lobes. When one lobe only is injured the affection of sight is hemiopic in monkeys: in this all observers agree.
On the whole, then, Munk's original location of vision in the occipital lobes is confirmed by the later evidence.[22] _In man_ we have more exact results, since we are not driven to interpret the vision from the outward conduct. On the other hand, however, we cannot vivisect, but must wait for pathological lesions to turn up. The pathologists who have discussed these (the literature is tedious _ad libitum_) conclude that the occipital lobes are the indispensable part for vision in man. Hemiopic disturbance in both eyes comes from lesion of either one of them, and total blindness, sensorial as well as psychic, from destruction of both.
Hemiopia may also result from lesion in other parts, especially the neighboring angular and supra-marginal gyri, and it may accompany extensive injury in the motor region of the cortex. In these cases it seems probable that it is due to an _actio in distans_, probably to the interruption of fibres proceeding from the occipital lobe.
There seem to be a few cases on record where there was injury to the occipital lobes without visual defect. Ferrier has collected as many as possible to prove his localization in the angular gyrus.[23] A strict application of logical principles would make one of these cases outweigh one hundred contrary ones. And yet, remembering how imperfect observations may be, and how individual brains may vary, it would certainly be rash for their sake to throw away the enormous amount of positive evidence for the occipital lobes. Individual variability is always a _possible_ explanation of an anomalous case. There is no more prominent anatomical fact than that of the 'decussation of the pyramids,' nor any more usual pathological fact than its consequence, that left-handed hemorrhages into the motor region produce right-handed paralyses. And yet the decussation is variable in amount, and seems sometimes to be absent altogether.[24] If, in such a case as this last, the left brain were to become the seat of apoplexy, the left and not the right half of the body would be the one to suffer paralysis.
The _schema_ below [Fig. 15], copied from Dr. Seguin, expresses, on the whole, the probable truth about the regions concerned in vision.
Not the entire occipital lobes, but the so-called cunei, and the first convolutions, are the cortical parts most intimately concerned.
Nothnagel agrees with Seguin in this limitation of the essential tracts.[25] * * * * * A most interesting effect of cortical disorder is _mental blindness_.
This consists not so much in insensibility to optical impressions, as in _inability to understand them_. Psychologically it is interpretable as _loss of associations_ between optical sensations and what they signify; and any interruption of the paths between the optic centres and the centres for other ideas ought to bring it about. Thus, printed letters of the alphabet, or words, signify certain sounds and certain articulatory movements. If the connection between the articulating or auditory centres, on the one hand, and the visual centres on the other, be ruptured we ought _a priori_ to expect that the sight of words would fail to awaken the idea of their sound, or the movement for pronouncing them. We ought, in short, to have _alexia_, or inability to read: and this is just what we do have in many cases of extensive injury about the fronto-temporal regions, as a complication of _aphasic_ disease. Nothnagel suggests that whilst the _cuneus_ is the seat of optical _sensations_, the other parts of the occipital lobe may be the field of optical _memories and ideas_, from the loss of which mental blindness should ensue. In fact, all the medical authors speak of mental blindness as if it must consist in the loss of visual images from the memory. It seems to me, however, that this is a psychological misapprehension. A man whose power of visual imagination has decayed (no unusual phenomenon in its lighter grades) is not mentally blind in the least, for he recognizes perfectly all that he sees. On the other hand, he _may_ be mentally blind, with his optical imagination well preserved; as in the interesting case published by Wilbrand in 1887.[26] In the still more interesting case of mental blindness recently published by Lissauer,[27] though the patient made the most ludicrous mistakes, calling for instance a clothes-brush a pair of spectacles, an umbrella a plant with flowers, an apple a portrait of a lady, etc. etc., he seemed, according to the reporter, to have his mental images fairly well preserved. It is in fact the momentary loss of our _non_-optical images which makes us mentally blind, just as it is that of our _non_-auditory images which makes us mentally deaf. I am mentally deaf if, _hearing_ a bell, I can't recall how it _looks_; and mentally blind if, _seeing_ it, I can't recall its _sound or its name_. As a matter of fact, I should have to be not merely mentally blind, but stone-blind, if all my visual images were lost. For although I am blind to the right half of the field of view if my left occipital region is injured, and to the left half if my right region is injured, such hemianopsia does not deprive me of visual _images_, experience seeming to show that the unaffected hemisphere is always sufficient for production of these. To abolish them entirely I should have to be deprived of both occipital lobes, and that would deprive me not only of my inward images of sight, but of my sight altogether.[28] Recent pathological annals seem to offer a few such cases.[29] Meanwhile there are a number of cases of mental blindness, especially for written language, coupled with hemianopsia, usually of the rightward field of